The First Battle of Newtonia was fought on September 30, 1862, between Confederate soldiers commanded by Colonel Douglas H. Cooper and a Union column commanded by Brigadier General Frederick Salomon near Newtonia, Missouri, during the American Civil War. Cooper's force had moved into southwestern Missouri, and encamped near the town of Newtonia. The Confederate column was composed mostly of cavalry led by Colonel Joseph O. Shelby and a brigade of Native Americans. A Union force commanded by Brigadier General James G. Blunt moved to intercept Cooper's force. Blunt's advance force, led by Salomon, reached the vicinity of Newtonia on September 29, and attacked Cooper's position on September 30. A Union probing force commanded by Colonel Edward Lynde was driven out of Newtonia by Cooper's forces on the morning of the 30th.

Douglas Hancock Cooper was an American politician, soldier, Indian Agent in what is now Oklahoma, and Confederate general during the American Civil War.