The First Brisbane Burial Ground is a heritage-listed archaeological site at Skew Street, Brisbane City, City of Brisbane, Queensland, Australia. It is also known as Skew Street Cemetery. It was established in 1825 as part of the Moreton Bay penal settlement. It was added to the Queensland Heritage Register on 16 July 2010.

Brisbane City is the central suburb and central business district of Brisbane, the state capital of Queensland, Australia. It is colloquially referred to as the "Brisbane CBD" or "the city". It is located on a point on the northern bank of the Brisbane River, historically known as Meanjin, Mianjin or Meeanjin in the local Aboriginal Australian dialect. The triangular shaped area is bounded by the median of the Brisbane River to the east, south and west. The point, known at its tip as Gardens Point, slopes upward to the north-west where the city is bounded by parkland and the inner city suburb of Spring Hill to the north. The CBD is bounded to the north-east by the suburb of Fortitude Valley. To the west the CBD is bounded by Petrie Terrace, which in 2010 was reinstated as a suburb.