The First Secretary of the Central Committee of the Communist Party of Cuba is the top leader of Cuba. The First Secretary is the highest office within the Communist Party of Cuba as well as ranking first in the Politburo, the highest decision-making body in Cuba, which makes the office holder the most powerful person in the Cuban government. In communist states the First or General Secretary of the Communist Party is typically the de facto leader of the country and a more powerful position than state offices such as President or Prime Minister, when those positions are held by different individuals.

Cuba, officially the Republic of Cuba, is an island country, comprising the island of Cuba, Isla de la Juventud, archipelagos, 4,195 islands and cays surrounding the main island. Cuba is located where the northern Caribbean Sea, Gulf of Mexico, and Atlantic Ocean meet. Cuba is located east of the Yucatán Peninsula (Mexico), south of both the American state of Florida and the Bahamas, west of Hispaniola, and north of Jamaica and the Cayman Islands. Havana is the largest city and capital. Cuba is the third-most populous country in the Caribbean after Haiti and the Dominican Republic, with about 11 million inhabitants.