The First Sjahrir Cabinet was the second Indonesian cabinet, named after the prime minister. It served from November 1945 to March 1946.

Sutan Sjahrir was an Indonesian politician, and revolutionary independence leader, who served as the first Prime Minister of Indonesia, from 1945 until 1947. Previously, he was a key Indonesian nationalist organizer in the 1930s and 1940s. Unlike some of his colleagues, he did not support the Japanese during the Japanese occupation and fought in the resistance against them. He was considered to be an idealist and an intellectual.