First ladies and gentlemen of Pakistan is an unofficial title traditionally given, often interchangeably, to the wife or husband of the president and prime minister of Pakistan. The current position First Ladies of Pakistan is Aseefa Bhutto Zardari, daughter of the former Prime Minister Benazir Bhutto and the current president Asif Ali Zardari. Along with their spouse and children, the First Lady or Gentleman is a member of the First Family of Pakistan.

Aseefa Bhutto Zardari is a Pakistani politician who is the current First Lady of Pakistan and a member of the National Assembly of Pakistan. She is the youngest daughter of Asif Ali Zardari, the current President of Pakistan, and Benazir Bhutto, the former Prime Minister of Pakistan.