Lake Victoria supports Africa's largest inland fishery, with the majority of present catch being the invasive Nile perch, introduced to the Lake in the 1950s. Prior to the introduction of Nile perch as well as Nile tilapia, the fish community was very different and consisted mainly of 'Ngege' and Victoria tilapia as well as vast numbers of Haplochromis species. Fish communities in the first half of the 20th century are known primarily from a unique fisheries survey conducted in 1927-1928 by the Colonial Office.

Lake Victoria is one of the African Great Lakes. With a surface area of approximately 59,947 km2 (23,146 sq mi), Lake Victoria is Africa's largest lake by area, the world's largest tropical lake, and the world's second-largest fresh water lake by surface area after Lake Superior in North America. In terms of volume, Lake Victoria is the world's ninth-largest continental lake, containing about 2,424 km3 (1.965×109 acre⋅ft) of water. Lake Victoria occupies a shallow depression in Africa. The lake has an average depth of 40 m (130 ft) and a maximum depth of 80–81 m (262–266 ft). Its catchment area covers 169,858 km2 (65,583 sq mi). The lake has a shoreline of 7,142 km (4,438 mi) when digitized at the 1:25,000 level, with islands constituting 3.7% of this length.