Flamingo is the southernmost headquarters of Everglades National Park, in Monroe County, Florida, United States. Flamingo is one of the two end points of the 99-mile (159-km) Wilderness Waterway, and the southern end of the only road through the park from Florida City. It began as a small coastal settlement on the eastern end of Cape Sable on the southern tip of the Florida peninsula, facing Florida Bay. The actual town of Flamingo was located approximately 4+1⁄2 miles west of the current Flamingo campground area. All that remains of the former town are a few remnants of building foundations, and it is considered a ghost town.

Monroe County is a county in the state of Florida. As of the 2020 census, the population was 82,874. Its county seat is Key West. Monroe County includes the islands of the Florida Keys and comprises the Key West-Key Largo Micropolitan Statistical Area. Over 99.9% of the county's population lives on the Florida Keys. The mainland, which is part of the Everglades, comprises 87% of the county's land area and is virtually uninhabited with only 17 people recorded in the 2020 census.