Florence is a town in Florence County, Wisconsin, United States. The population was 2,319 at the 2000 census. The ZIP code is 54121. Florence is also the name of a census-designated place within the town about 11 miles (18 km) northwest of Iron Mountain, Michigan; the community is the county seat of Florence County. The unincorporated communities of Hematite, Pulp, Ridgetop, Spread Eagle, and Tyran are also located in the town.

Florence County is a county located in the U.S. state of Wisconsin. As of the 2020 census, the population was 4,558, making it the second-least populous county in Wisconsin after Menominee County. Its county seat is Florence.