Flywheel, Shyster, and Flywheel is a situation comedy radio show starring two of the Marx Brothers, Groucho and Chico, and written primarily by Nat Perrin and Arthur Sheekman. The series was originally broadcast in the United States on the National Broadcasting Company's Blue Network, beginning on November 28, 1932, and ending on May 22, 1933. Sponsored by the Standard Oil Companies of New Jersey, Pennsylvania and Louisiana and the Colonial Beacon Oil Company, it was the Monday night installment of the Five-Star Theater, an old-time radio variety series that offered a different program each weeknight. Episodes were broadcast live from NBC's WJZ station in New York City and later from a sound stage at RKO Pictures in Los Angeles, California, before returning to WJZ for the final episodes.

The Marx Brothers were an American family comedy act that was successful in vaudeville, on Broadway, and in 14 motion pictures from 1905 to 1949. Five of the Marx Brothers' fourteen feature films were selected by the American Film Institute (AFI) as among the top 100 comedy films, with two of them, Duck Soup (1933) and A Night at the Opera (1935), in the top fifteen. They are widely considered by critics, scholars and fans to be among the greatest and most influential comedians of the 20th century. The brothers were included in AFI's 100 Years... 100 Stars list of the 25 greatest male stars of Classical Hollywood cinema, the only performers to be included collectively.