The secretary of state for foreign, commonwealth and development affairs, also known as the foreign secretary, is a secretary of state in the Government of the United Kingdom, with responsibility for the Foreign, Commonwealth and Development Office. The role is seen as one of the most senior ministers in the UK Government and is a Great Office of State. The incumbent is a member of the Cabinet of the United Kingdom and National Security Council, and reports directly to the prime minister.

His Majesty's principal secretaries of state, or secretaries of state, are senior ministers of the Crown in the Government of the United Kingdom. Secretaries of state head most major government departments and make up the majority of the Cabinet of the United Kingdom.