Fort Randall Dam is a 2.03-mile-long (3 km) earthen dam which spans the Missouri River and impounds Lake Francis Case, the 11th-largest reservoir in the U.S. The dam joins Gregory and Charles Mix counties, South Dakota a distance of 880 river miles (1,416 km) upstream of St. Louis, Missouri, where the river joins the Mississippi River. The dam and hydroelectric power plant were constructed by and are currently operated by the U.S. Army Corps of Engineers.

The 2011 flooding event on the Missouri River in the United States was triggered by record snowfall in Rocky Mountains of Montana and Wyoming along with near-record spring rainfall in central and eastern Montana. All six major dams along the Missouri River released record amounts of water to prevent overflow which led to flooding threatening several towns and cities along the river from Montana to Missouri; in particular Bismarck, North Dakota; Pierre, South Dakota; Dakota Dunes, South Dakota; South Sioux City, Nebraska, Sioux City, Iowa; Omaha, Nebraska; Council Bluffs, Iowa; Saint Joseph, Missouri; Kansas City, Missouri; Jefferson City, Missouri, and St. Louis, Missouri. Many smaller towns were also at risk, suffering the same fate as the larger cities if not worse. According to the National Weather Service, in the second half of the month of May 2011, almost a year's worth of rain fell over the upper Missouri River basin. Extremely heavy rainfall in conjunction with an estimated 212 percent of normal snowpack in the Rocky Mountains contributed to this flooding event.