Francis II was Duke of Brittany from 1458 to his death. He was the grandson of John IV, Duke of Brittany. A recurring theme in Francis' life would be his quest to maintain the quasi-independence of Brittany from France. As such, his reign was characterized by conflicts with King Louis XI of France and with his daughter, Anne of France, who served as regent during the minority of her brother, King Charles VIII. The armed and unarmed conflicts from 1465 to 1477 and 1484–1488 have been called the "War of the Public Weal" and the Mad War, respectively.

The Duchy of Brittany was a medieval feudal state that existed between approximately 939 and 1547. Its territory covered the northwestern peninsula of Europe, bordered by the Atlantic Ocean to the west, and the English Channel to the north. It was also less definitively bordered by the river Loire to the south, and Normandy, and other French provinces, to the east. The Duchy was established after the expulsion of Viking armies from the region around 939. The Duchy, in the 10th and 11th centuries, was politically unstable, with the dukes holding only limited power outside their own personal lands. The Duchy had mixed relationships with the neighbouring Duchy of Normandy, sometimes allying itself with Normandy, and at other times, such as the Breton–Norman War, entering into open conflict.