Francis Lewis Boulevard is a boulevard in the New York City borough of Queens. The roadway is named for Francis Lewis, a Queens resident who was a signer of the United States Declaration of Independence. The boulevard zigzags across Queens by including segments of several other roadways that were renamed to become parts of the boulevard.

Francis Lewis was an American merchant and a Founding Father of the United States. He was a signatory of the United States Declaration of Independence and Articles of Confederation as a representative of New York in the Continental Congress.