Francis Godolphin Osborne, 1st Baron Godolphin, styled Lord Francis Osborne from 1789 to 1832, was a British politician.

Francis Godolphin Osborne, 5th Duke of Leeds,, styled Marquess of Carmarthen until 1789, was a British politician. He notably served as Foreign Secretary under William Pitt the Younger from 1783 to 1791. He also was Governor of Scilly. In 1790, he was made a Knight of the Order of the Garter. As a statesman, he is generally regarded as a failure, and his deep hostility to the newly independent United States damaged relations between the two countries.