Francis Preston Blair Jr. was a United States Senator, a United States Congressman and a Union Major General during the Civil War. He represented Missouri in both the House of Representatives and the Senate, and was active in preventing the State of Missouri from being absorbed into the Confederacy at the beginning of the Civil War.

Nathaniel Lyon was a United States Army officer who was the first Union general to be killed in the American Civil War. He is noted for his actions in Missouri in 1861, at the beginning of the conflict, to forestall secret secessionist plans of the governor Claiborne Jackson.