Francis Xavier "Frank" Pembleton is a fictional homicide detective on the television drama series Homicide: Life on the Street portrayed by Emmy Award–winning actor Andre Braugher. He is a primary character of the show through the first six seasons. Although the show featured an ensemble cast, Pembleton would become the fan-favorite and is often identified by as the show's signature character. He is based on Baltimore Police Department Detective Harry Edgerton, who, like Pembleton, was an eccentric New York–born African American detective in the BPD homicide unit featured in David Simon's book Homicide: A Year on the Killing Streets. The character also appeared in the Law & Order episode "Charm City".

Homicide: Life on the Street is an American police drama television series chronicling the work of a fictional version of the Baltimore Police Department's Homicide Unit. Created by Paul Attanasio, it ran for seven seasons and 122 episodes on NBC from January 31, 1993, to May 21, 1999, and was succeeded by Homicide: The Movie (2000), which served as the series finale. The series was created by Paul Attanasio and based on David Simon's book Homicide: A Year on the Killing Streets (1991). Many of the characters and stories used throughout the show were based on events depicted in the book.