Frank Zappa Meets the Mothers of Prevention is a 1985 album by American musician Frank Zappa. The album was originally released in two slightly different versions in the US and Europe.

The Parents Music Resource Center (PMRC) was an American committee formed in 1985 with the stated goal of increasing parental control over the access of children to music deemed to have violent, drug-related, or sexual themes via labeling albums with Parental Advisory stickers. The committee was founded by four women known as the "Washington Wives"—a reference to their husbands' connections with government in the Washington, D.C. area. The women who founded the PMRC are Tipper Gore, wife of Senator and later Vice President Al Gore; Susan Baker, wife of Treasury Secretary James Baker; Pam Howar, wife of Washington realtor Raymond Howar; and Sally Nevius, wife of former Washington City Council Chairman John Nevius. The PMRC eventually grew to include 22 participants before shutting down in the mid-to-late 1990s.