Frankenhooker is a 1990 American black comedy horror film directed by Frank Henenlotter. Very loosely inspired by Mary Shelley's 1818 novel Frankenstein; or, The Modern Prometheus, the film stars James Lorinz as medical school drop-out Jeffrey Franken and former Penthouse Pet Patty Mullen as the title character.

Frank Henenlotter is an American film director, screenwriter and film historian. He is known primarily for directing horror comedies, especially Basket Case (1982), Brain Damage (1988), and Frankenhooker (1990).