Frankenstein's Monster is a fictional character appearing in American comic books published by Marvel Comics. The character is based on the character in Mary Shelley's 1818 novel Frankenstein; or, The Modern Prometheus. The character has been adapted often in the comic book medium.

The Marvel Universe is a fictional shared universe where the stories in most American comic book titles and other media published by Marvel Comics take place. Super-teams such as the Avengers, the X-Men, the Fantastic Four, the Guardians of the Galaxy, and many Marvel superheroes live in this universe, including characters such as Spider-Man, Captain America, Iron Man, Thor, the Hulk, Ant-Man, the Wasp, Wolverine, Black Panther, Doctor Strange, Daredevil, and Captain Marvel, Blade, Black Widow, Hawkeye, among numerous others. It also contains well-known supervillains such as Doctor Doom, Magneto, Ultron, Thanos, Loki, The Green Goblin, Kang the Conqueror, Red Skull, The Kingpin, Doctor Octopus, Carnage, Apocalypse, Dormammu, Mysterio, Electro, and the Vulture. It also contains antiheroes such as Venom, Namor, Deadpool, Silver Sable, Ghost Rider, The Punisher, and Black Cat.