Frankfurt (Main) Airport regional station is an underground railway station at Frankfurt Airport in Frankfurt, Germany. It provides local S-Bahn and Regionalbahn services to the city and the Frankfurt/Rhine-Main Metropolitan Region. The station opened on 14 March 1972 together with a new passenger terminal. At the time it was only the second railway station serving an airport in Germany.

Frankfurt Airport, German: Flughafen Frankfurt Main, is Germany's main international airport by passenger numbers, located in Frankfurt, Germany's fifth-largest city. In the German Aeronautical Information Publication, its name is Frankfurt Main Airport. The airport is operated by Fraport and serves as the main hub for Lufthansa, including Lufthansa CityLine and Lufthansa Cargo as well as Condor and AeroLogic. It covers an area of 2,300 hectares of land and features two passenger terminals with capacity for approximately 65 million passengers per year; four runways; and extensive logistics and maintenance facilities.