Frederick Stephen Upton is an American politician who served as a U.S. representative from Michigan from 1987 to 2023, representing the state's 6th congressional district since 1993. He is a member of the Republican Party. His district, numbered as the 4th district from 1987 to 1993, was based in Kalamazoo and stretched along the Michigan-Indiana border in the southwestern part of the state.

Michigan's 6th congressional district is a United States congressional district in southeast Michigan. In 2022, the district was redrawn to be centered around Ann Arbor and Washtenaw County, as well as western and southern Wayne County, small part of southwestern Oakland County, and the city of Milan in Monroe County. In previous redistrictings, the 6th district consisted of all of Berrien, Cass, Kalamazoo, St. Joseph, and Van Buren, counties, and includes most of Allegan county.