The Frederick Douglass National Historic Site, administered by the National Park Service, is located at 1411 W Street, SE, in Anacostia, a neighborhood east of the Anacostia River in Southeast Washington, D.C. United States. Established in 1988 as a National Historic Site, the site preserves the home and estate of Frederick Douglass, one of the most prominent African Americans of the 19th century. Douglass lived in this house, which he named Cedar Hill, from 1877–1878 until his death in 1895. Perched on a hilltop, the site offers a sweeping view of the U.S. Capitol and the Washington, D.C., skyline.

Anacostia is a historic neighborhood in Southeast Washington, D.C. Its downtown is located at the intersection of Good Hope Road and Martin Luther King Jr. Avenue. It is located east of the Anacostia River, after which the neighborhood is named.