Frederiksholms Kanal is a canal in central Copenhagen, Denmark, which runs along the south-west side of Slotsholmen, together with Slotsholmskanalen separating the island from Zealand. The name also applies to the continuation of Rådhusstræde which follows the canal for most of its course, first on its south side and for the last stretch, from Prinsens Bro and to the waterfront, on both sides of the canal. Several historic buildings face the canal, ranging in size from Prince's Mansion, now housing National Museum, and Christiansborg's riding grounds to the diminutive Stable Boy's House, part of Civiletatens Materialgård, a former storage facility now used by the Royal Danish Academy of Fine Arts's School of Sculpture.

Slotsholmen is an island in the harbour of Copenhagen, Denmark, and part of Copenhagen Inner City. The name is taken from the successive castles and palaces located on the island since Bishop Absalon constructed the city's first castle on the island in 1167 at the site where Christiansborg Palace lies today.