Friedrichshain is a quarter (Ortsteil) of the borough of Friedrichshain-Kreuzberg in Berlin, Germany. From its creation in 1920 until 2001, it was a freestanding city borough. Formerly part of East Berlin, it is adjacent to Mitte, Prenzlauer Berg, Kreuzberg and Lichtenberg.

Berlin is both a city and one of Germany's federated states. Since the 2001 administrative reform, it has been made up of twelve districts, each with its own administrative body. However, unlike the municipalities and counties of other German states, the Berlin districts are not territorial corporations of public law with autonomous competencies and property, but simple administrative agencies of Berlin's state and city government, the City of Berlin forming a single municipality since the Greater Berlin Act of 1920. Thus they cannot be equated to US or UK boroughs in the traditional meaning of the term.