The Friedrichstraße is a major culture and shopping street in central Berlin, forming the core of the Friedrichstadt neighborhood and giving the name to Berlin Friedrichstraße station. It runs from the northern part of the old Mitte district to the Hallesches Tor in the district of Kreuzberg.

Friedrichstadt was an independent suburb of Berlin, and is now a historical neighbourhood of the city itself. The neighbourhood is named after the Prussian king Frederick I.