Friendship Cemetery is a cemetery located in Columbus, Mississippi. In 1849, the cemetery was established on 5 acres by the Independent Order of Odd Fellows. The original layout consisted of three interlocking circles, signifying the Odd Fellows emblem. By 1957, Friendship Cemetery had increased in size to 35 acres, and was acquired by the City of Columbus. The cemetery was listed on the National Register of Historic Places in 1980 and was designated a Mississippi Landmark in 1989. As of 2015, the cemetery contained some 22,000 graves within an area of 70 acres and was still in use. The Mississippi School for Mathematics and Science hosts a public event every April at night in the cemetery. Students complete a research project on someone buried at the school, before dressing up and doing a performance as the person they researched.

William Barksdale was a lawyer, newspaper editor, US Representative, and Confederate general in the American Civil War. He served four terms in the U.S. House of Representatives from 1853 to 1861.