Friendship Cemetery is a cemetery located in Columbus, Mississippi. In 1849, the cemetery was established on 5 acres by the Independent Order of Odd Fellows. The original layout consisted of three interlocking circles, signifying the Odd Fellows emblem. By 1957, Friendship Cemetery had increased in size to 35 acres, and was acquired by the City of Columbus. The cemetery was listed on the National Register of Historic Places in 1980 and was designated a Mississippi Landmark in 1989. As of 2015, the cemetery contained some 22,000 graves within an area of 70 acres and was still in use. The Mississippi School for Mathematics and Science hosts a public event every April at night in the cemetery. Students complete a research project on someone buried at the school, before dressing up and doing a performance as the person they researched.

Columbus is a city in and the county seat of Lowndes County, on the eastern border of Mississippi, United States, located primarily east, but also north and northeast of the Tombigbee River, which is also part of the Tennessee-Tombigbee Waterway. It is approximately 146 miles (235 km) northeast of Jackson, 92 miles (148 km) north of Meridian, 63 miles (101 km) south of Tupelo, 60 miles (97 km) northwest of Tuscaloosa, Alabama, and 120 miles (193 km) west of Birmingham, Alabama.