Galileo Academy of Science and Technology, formerly known as Galileo High School, is a public high school located between the Russian Hill and Marina District neighborhoods of San Francisco, California. The school is a part of the San Francisco Unified School District.

San Francisco Unified School District (SFUSD), established in 1851, is the only public school district within the City and County of San Francisco, and the first in the state of California. Under the management of the San Francisco Board of Education, the district serves approximately 49,500 students across 121 schools.