Gamaliel is a home rule-class city in Monroe County, Kentucky, in the United States. The population was 391 at the 2020 census.

Monroe County is a county located in the Eastern Pennyroyal Plateau region of the U.S. state of Kentucky. Its county seat is Tompkinsville. The county is named for President James Monroe. It was a prohibition or dry county until November 7, 2023, when voters approved the sale of alcohol.