The Ganges shark is a critically endangered species of requiem shark found in the Ganges River and the Brahmaputra River of India and Bangladesh. It is often confused with the more common bull shark, which also inhabits the Ganges River and is sometimes incorrectly referred to as the Ganges shark. The genus is currently considered to contain three recent species; genetic evidence has shown that both the Borneo river shark and Irrawaddy river shark should be regarded as synonyms of the Ganges shark, expanding the range of the species to Pakistan, Myanmar, Borneo, and Java. While the other members of the genus Glyphis occur in coastal marine waters as well as rivers, the Ganges shark is found only in fresh water, making it the world's only exclusively freshwater shark. The species remains poorly known and very rare.

Requiem sharks are sharks of the family Carcharhinidae in the order Carcharhiniformes. They are migratory, live-bearing sharks of warm seas and include such species as the bull shark, lemon shark, spinner shark, blacknose shark, blacktip shark, grey reef shark, blacktip reef shark, silky shark, dusky shark, blue shark, copper shark, oceanic whitetip shark, and whitetip reef shark.