Garden City, sometimes known as Garden City Beach, is a census-designated place (CDP) in Horry County, South Carolina, United States. The population was 9,209 at the 2010 census. Garden City Beach is located directly south of Surfside Beach. The developed part of the beach extends south beyond the limits of the Garden City CDP, into Georgetown County, and ends on a peninsula at the mouth of Murrells Inlet.

Horry County is the easternmost county in the U.S. state of South Carolina. As of the 2020 census, its population was 351,029. It is the fourth-most populous county in South Carolina. The county seat is Conway.