The Garden City Skyway is a major high-level bridge located in St. Catharines and Niagara-on-the-Lake, Ontario, Canada, that allows the Queen Elizabeth Way (QEW) to cross the Welland Canal without the interruption of a lift bridge. Six lanes of traffic are carried across the bridge, which is 2.2 kilometres (1.4 mi) in length and 40 metres (130 ft) at its tallest point.

St. Catharines is the most populous city in Canada's Niagara Region, the eighth largest urban area in the province of Ontario. As of 2017, St. Catharines has an area of 96.13 square kilometres (37.12 sq mi) and 140,370 residents. It lies in Southern Ontario, 51 kilometres (32 mi) south of Toronto across Lake Ontario, and is 19 kilometres (12 mi) inland from the international boundary with the United States along the Niagara River. It is the northern entrance of the Welland Canal. Residents of St. Catharines are known as St. Catharinites. St. Catharines carries the official nickname "The Garden City" due to its 1,000 acres (4 km2) of parks, gardens, and trails.