During the Israel–Hamas war, the Israeli military ordered most residents of Gaza to evacuate their homes, displacing hundreds of thousands of people and contributing to a broader humanitarian crisis in the territory. It is the largest displacement of Palestinians in 75 years. Palestinians have described the evacuation as the "second Nakba."

The Gaza Strip is experiencing a humanitarian crisis as a result of the Israel–Hamas war. The crisis includes both a famine and a healthcare collapse. At the start of the war, Israel tightened its blockade on the Gaza Strip, which has resulted in significant shortages of fuel, food, medication, water, and essential medical supplies. This siege resulted in a 90% drop in electricity availability, impacting hospital power supplies, sewage plants, and shutting down the desalination plants that provide drinking water. Widespread disease outbreaks have spread across Gaza.