George Combe was a Scottish lawyer and a spokesman of the phrenological movement for over 20 years. He founded the Edinburgh Phrenological Society in 1820 and wrote The Constitution of Man (1828). After marriage in 1833, Combe devoted his later years to promoting phrenology internationally.

Phrenology or Craniology is a pseudoscience that involves the measurement of bumps on the skull to predict mental traits. It is based on the concept that the brain is the organ of the mind, and that certain brain areas have localized, specific functions or modules. It was said that the brain was composed of different muscles, so those that were used more often were bigger, resulting in the different skull shapes. This led to the reasoning behind why everyone had bumps on the skull in different locations. The brain "muscles" not being used as frequently remained small and were therefore not present on the exterior of the skull. Although both of those ideas have a basis in reality, phrenology generalizes beyond empirical knowledge in a way that departs from science. The central phrenological notion that measuring the contour of the skull can predict personality traits is discredited by empirical research. Developed by German physician Franz Joseph Gall in 1796, the discipline was influential in the 19th century, especially from about 1810 until 1840. The principal British centre for phrenology was Edinburgh, where the Edinburgh Phrenological Society was established in 1820.