Francis Stewart, 5th Earl of Bothwell, was Commendator of Kelso Abbey and Coldingham Priory, a Privy Counsellor and Lord High Admiral of Scotland. He was a notorious conspirator who led several uprisings against his first cousin, King James VI, all of which ultimately failed, and he died in poverty in Italy after being banished from Scotland. Francis's maternal uncle, the 4th Earl of Bothwell, was the chief suspect in the murder of James VI's father, Lord Darnley.
Bothwell had part of Crichton Castle rebuilt in the Italian Renaissance style, c. 1585