George Mathews was an American soldier and politician from the U.S. States of Virginia and Georgia. He was a brevet brigadier general in the Continental Army, the 20th and 24th Governor of Georgia, a U.S. Representative from Georgia, and the leading participant in the Patriot War of East Florida.

The Patriot War was an attempt in 1812 to foment a rebellion in Spanish East Florida with the intent of annexing the province to the United States. The invasion and occupation of parts of East Florida had elements of filibustering, but was also supported by units of the United States Army, Navy and Marines, and by militia from Georgia and Tennessee. The rebellion was instigated by General George Mathews, who had been commissioned by United States President James Madison to accept any offer from local authorities to deliver any part of the Floridas to the United States, and to prevent the reoccupation of the Floridas by Great Britain. The rebellion was supported by the Patriot Army, which consisted primarily of citizens of Georgia. The Patriot Army, with the aid of U.S. Navy gunboats, was able to occupy Fernandina and parts of northeast Florida, but never gathered enough strength to attack St. Augustine. United States Army troops and Marines were later stationed in Florida in support of the Patriots. The occupation of parts of Florida lasted over a year, but after United States military units were withdrawn and Seminoles entered the conflict, the Patriots dissolved.