George Nixon Briggs was an American lawyer and politician from Massachusetts. A Whig, Briggs served for twelve years in the United States House of Representatives, and served seven one-year terms as the 19th Governor of Massachusetts, from 1844 to 1851.

After Boston businessman George Parkman disappeared in November 1849, his dismembered and partially burned body was found in the laboratory of John Webster, a lecturer at Harvard Medical College; Webster was convicted of Parkman's murder and hanged. Highly publicized because of its gruesome nature and the high social status of Parkman and Webster, the case was one of the earliest in which forensic evidence was used to identify a body.