State Route 52 (SR 52) is a 124.697-mile-long (200.680 km) state highway that travels west to east through portions of Whitfield, Murray, Gilmer, Dawson, Lumpkin, Hall, Banks, and Jackson counties in the northern part of the U.S. state of Georgia. The highway extends from its western terminus at Interstate 75 (I-75) in Dalton to its eastern terminus at SR 98 in Maysville.

Whitfield County is a county located in the northwestern part of the U.S. state of Georgia. As of the 2020 census shows a population of 102,864. The county seat is Dalton. The county was created on December 30, 1851, and named after George Whitefield, Methodist evangelist. The "e" was omitted to reflect the pronunciation of his name.