State Route 99 (SR 99) is a 38.9-mile-long (62.6 km) state highway that travels south-to-north through portions of Glynn and McIntosh counties in the southeastern part of the U.S. state of Georgia. The highway begins at its southern terminus at US 82/SR 520 southwest of Sterling to its northern terminus at I-95 and SR 57 in Eulonia. The Ridge in Ridgeville on SR 99 is listed on the National Register of Historic Places.

Glynn County is located in the southeastern part of the U.S. state of Georgia. As of the 2020 census, the population was 84,499. The county seat is Brunswick. Glynn County is part of the Brunswick, Georgia Metropolitan Statistical Area.