Gesso, also known as "glue gesso" or "Italian gesso", is a white paint mixture used to coat rigid surfaces such as wooden painting panels or masonite as a permanent absorbent primer substrate for painting. It consists of a binder mixed with chalk, gypsum, pigment, or any combination of these.

Gypsum is a soft sulfate mineral composed of calcium sulfate dihydrate, with the chemical formula CaSO4·2H2O. It is widely mined and is used as a fertilizer and as the main constituent in many forms of plaster, drywall and blackboard or sidewalk chalk. Gypsum also crystallizes as translucent crystals of selenite. It forms as an evaporite mineral and as a hydration product of anhydrite. The Mohs scale of mineral hardness defines gypsum as hardness value 2 based on scratch hardness comparison.