A giant virus, sometimes referred to as a girus, is a very large virus, some of which are larger than typical bacteria. All known giant viruses belong to the phylum Nucleocytoviricota.
Cryo-EM images of the giant viruses CroV and APMV. (A) Cryo-electron micrograph of four CroV particles. (B) Single CroV particle with concave core depression (white arrow). (C) Single APMV particle. Scale bars in (A–C) represent 2,000 Å.
Several giant viruses (Megaklothovirus horridgei, Pithovirus sibericum, Klothovirus casanovai, and Mimivirus) compared to E. Coli bacterium and normal size virus (HIV)