Gibson County is a county located in the U.S. state of Tennessee. As of the 2020 census, the population was 50,429. Its county seat is Trenton. The county was formed in 1823 and named for John H. Gibson, a soldier of the Natchez Expedition and the Creek War.

Trenton is the county seat and fourth largest city of Gibson County, Tennessee, United States. As of the 2020 census, the population was 4,240.