Gifford is an unincorporated community and census-designated place (CDP) in Indian River County, Florida, United States. It is part of the Sebastian–Vero Beach Metropolitan Statistical Area. The population was 5,511 at the 2020 census. Gifford has a rich African American history and is noted as the hometown of several African-American landscape artists who were members of The Highwaymen. Gifford is one of the poorest communities in Florida.

Indian River County is a county located in the southeastern and east-central portions of the U.S. state of Florida. As of the 2020 census, the population was 159,788. Its seat is Vero Beach. It is Florida's 7th richest county and in 2000 was the 87th richest county in the U.S. by per capita income.