The Giro di Castelbuono is an annual road running competition over 10 kilometres which takes place in Castelbuono, on the island of Sicily, Italy. First held in 1912, the competition, which holds IAAF Gold Label Road Race status, is one of the oldest road races in Europe, which is the inspiration for the event's nickname – "La Corsa Più Antica". The race, typically held on July 26 to coincide with Saint Anne's Day, has been held almost every year since its inauguration, although the two World Wars interrupted the event over those periods. The race has been broadcast every year for a decade by Italian television channel Rai Sport Più.

Castelbuono is a town and comune in the Metropolitan City of Palermo, Sicily.