Goldsboro is a town in Caroline County, Maryland, United States. William James Yeager is the current mayor. The population was 246 at the 2010 United States Census. The zip code is 21636. First known as Oldtown, it was renamed in 1870 for the prominent Goldsborough family who owned land in the area. Castle Hall was listed on the National Register of Historic Places in 1975.

Caroline County is a rural county located in the U.S. state of Maryland on its Eastern Shore. As of the 2020 census, the population was 33,293. Its county seat is Denton.