Goulburn Valley Highway is a highway located in Victoria, Australia. The section north of the Hume Freeway is part of the Melbourne to Brisbane National Highway and is the main link between these two cities as well as a major link between Victoria and inland New South Wales. It is also the most direct route between Melbourne and the major regional centre of Shepparton in Victoria.

The National Highway is a system of roads connecting all mainland states and territories of Australia, and is the major network of highways and motorways connecting Australia's capital cities and major regional centres.