Government Medical College Thrissur is a government medical school situated in the city of Thrissur in the Indian state of Kerala.

Thrissur, formerly Trichur, also known by its historical name Thrissivaperur, is a city and the headquarters of the Thrissur district in Kerala, India. It is the third largest urban agglomeration in Kerala after Kochi and Kozhikode, and the 21st largest in India. The city is built around a 65-acre (26 ha) hillock called the Thekkinkaadu Maidaanam which seats a large Hindu Shiva Temple. It is located 304 kilometres (189 mi) north-west of the state's capital city, Thiruvananthapuram. Thrissur was once the capital of the Kingdom of Cochin, and was a point of contact for the Assyrians, Greeks, Persians, Arabs, Romans, Portuguese, Dutch and English.