Government Street Presbyterian Church in Mobile, Alabama is one of the oldest and least-altered Greek Revival church buildings in the United States. The architectural design is by James Gallier Sr., James H. Dakin, and Charles Dakin. The trio also designed Barton Academy, four blocks down Government Street to the west. Government Street Presbyterian reflects the influences of Ithiel Town, Minard Lafever, and Andrew Jackson Downing. It was declared a National Historic Landmark in 1992.

James Gallier was a prominent nineteenth-century Irish-born American architect, most famed for his buildings in New Orleans. Gallier Hall, which he designed and once served as New Orleans City Hall, is named after him.