The Government of San Diego County is defined and authorized under the California Constitution, California law, and the Charter of the County of San Diego. Much of the Government of California is in practice the responsibility of county governments such as the Government of San Diego County. The County government provides countywide services such as elections and voter registration, law enforcement, jails, vital records, property records, tax collection, public health, and social services. In addition the County serves as the local government for all unincorporated areas.

San Diego County, officially the County of San Diego, is a county in the southwestern corner of the U.S. state of California. As of the 2020 census, the population was 3,298,634, making it California's second-most populous county and the fifth-most populous in the United States. Its county seat is San Diego, the second-most populous city in California and the eighth-most populous city in the United States. It is the southwesternmost county in the 48 contiguous United States, and is a border county. It is also home to 18 Native American tribal reservations, the most of any county in the United States.