Venezuela is a federal presidential republic. The chief executive is the President of Venezuela who is both head of state and head of government. Executive power is exercised by the President. Legislative power is vested in the National Assembly of Venezuela. Supreme judicial power is exercised by the Supreme Tribunal of Justice.

The Ministry of Economy and Finance is a ministry of the government of Venezuela with similar portfolios dating back to 1810 with the creation of a tax office. When Gran Colombia was dissolved and Venezuela assumed its independence, the Ministry of Finance was created in 1830 when General José Antonio Páez commissioned the establishment of the public business office to three Secretariats of State: Interior, Justice and Police, War and Navy, Finance, and Foreign Relations. The current minister has been Delcy Rodríguez since September 2020.