The Grão-Pará Ecological Station (Portuguese: Estação Ecológica Grão-Pará is a strictly protected ecological station in the state of Pará, Brazil. It managed by the state of Pará. With 42,458 square kilometres of well-preserved Amazon rainforest it is the largest fully protected tropical forest conservation unit in the world.

An ecological station in Brazil is a type of protected area of Brazil as defined by the National System of Conservation Units (SNUC). The purpose is to preserve untouched representative samples of the different biomes in Brazil.